U0880-02
UbcH7, Recombinant, Human (Ubiquitin-conjugating enzyme E2 L3, UBE2L3, Ubiquitin-conjugating enzyme E2-F1, L-UBC, Ubiquitin carrier protein L3, Ubiquitin protein ligase L3)
Size
£819.00
- SKU:
- U0880-02
- Molecular Weight:
- 17.9
- Purity:
- ~95% (SDS PAGE) Purified by conventional chromatography techniques.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Format:
- Supplied as a liquid in 50mM HEPES, pH 7.5, 150mM sodium chloride, 1mM DTT and 10% glycerol.
- Extra Details:
- Human Ubquitin-conjugating enzyme 7 (UbcH7) is a ubiquitin-conjugating enzyme (E2) mediating c-fos degradation, transcription factor NF-kB maturation, and human papilloma virus-mediated p53 and Myc protein degradation, in vitro. The ubiquitin-conjugating enzymes (E2s) are essential components of the post-translational protein ubiquitination pathway, mediating the transfer of activated ubiquitin to substrate proteins. The human UBE2L1-UBE2L4 gene could potentially encode different isoforms of the UbcH7. UBE2L3 gene, located at chromosome 22q11.2, is the only identical family member with introns and encodes a polypeptide sequence identical to that of UbcH7 (NP_003338). Molecular Weight: 17.9kD (154 amino acids). Does not contain His tag. AA Sequence: MAASRRLMKE LEEIRKCGMK NFRNIQVDEA NLLTWQGLIV PDNPPYDKGA FRIEINFPAE YPFKPPKITF KTKIYHPNID EKGQVCLPVI SAENWKPATK TDQVIQSLIA LVNDPQPEHP LRADLAEEYS KDRKKFCKNA EEFTKKYGEK RPVD Enzyme Activity: Not determined. This product is recommended for use in applications that do not require a catalytically active form of the protein. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice