TZFP (FAZF, Zinc Finger and BTB Domain-containing Protein 32, FANCC-interacting Protein, Fanconi Anemia Zinc Finger Protein, Testis Zinc Finger Protein, Zinc Finger Protein 538, ZBTB32, ZNF538)

Size

£642.00

SKU:: T9950-50B
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Goat
Immunogen:: Synthetic peptide corresponding to RPSTSPCCPSSSTT from the C-terminal of human TZFP.
Format:: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Extra Details:: DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Peptide ELISA: 1:8000 Western Blot: 2-5ug/ml ~55kD band observed in human bone marrow lysates Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.