T9155-10
Tubulin, beta 3 (Tubulin beta III, TUBB 3, TUBB3, Neuron Specific beta III Tubulin, beta-4, MC1R, Tubulin beta 4, TUBB 4)
Size
£895.00
- SKU:
- T9155-10
- Purity:
- Ascites
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Synthetic peptide corresponding to amino acids 443-450, ESESQGPK, of human class 3 beta-tubulin conjugated to KLH. Epitope: C-terminus.
- Clone:
- 2Q121 (TU-20)
- Format:
- Supplied as a liquid in PBS, 1% BSA, 15mM sodium azide.
- Extra Details:
- Class 3 beta tubulin (beta 3-tubulin) is a vertebrate tubulin Isotype specific to the neurons and mammalian testis cells, making it an ideal neuronal marker. Overexpression of class 3 beta tubulin is associated with the resistances of microtubule- targeted cancer drugs in lung cancer cell lines, breast cancer cell lines, and ovarian tumors. Applications: Suitable for use in Immunoprecipitation, Immunocytochemistry, Immunohistochemistry, Western Blot and ELISA. Other applications have not been tested. Recommended Dilutions: Immunocytochemistry (Fixed): 1:100-1:500. Immunohistochemistry (FFPE): 1:20-1:100. Requires HIER using sodium citrate buffer pH6.0 prior to staining. Western Blot: 1:1000. Optimal dilutions to be determined by the researcher. Positive Control: Brain tissue or neurons of any type. Negative Control: Non-neuronal tissue or Astrocytes. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice