Tubby (TUB, F10B5.4, Retinal Degeneration 5, RD5) (Not for Export EU)

Size

£581.00

SKU:: T9152-51
Purity:: Whole antisera
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: A recombinant Tubby protein (domain residues 160-421).
Format:: As reported
Extra Details:: Tub-1 protein is C. elegans tubby homolog, required for normal sensory behavior. It is expressed in ciliated neurons and undergoes both cilated and dendritic transport. It has been shown to be involved in regulating fat storage, most likely by modulating transport, sensing, or responding to signals in ciliated neurons. It has also been shown to play a role in regulating life span, but by a different mechanism than fat storage regulation. Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Western Blot: 1:1000. The molecular weight of this protein as seen in Western blot is 48-50kD. Optimal dilutions to be determined by the researcher. Cellular Localization: Cytoplasmic Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 3 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.