Troponin I, Cardiac, Human (Troponin I, Cardiac Muscle, Cardiac Troponin I, TNNI3, TNNC1)

Size

£698.00

SKU:: T8665-18Q
Purity:: ≥95% (SDS PAGE).
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 20mM Tris, 7M Urea, 5mM EDTA, 15mM mercaptoethanol.
Extra Details:: Human cardiac troponin I is the inhibitory subunit of troponin involved in confering calcium sensitivity to muscle actomyosin ATPase activity. Mutation of the TNN13 gene can lead to familial hypotrophic cardiomyopathy 7 (CMH7), a hereditary heart condition characterized by asymetric ventricular hypertrophy (Kimura et al. 1997). Other cardiomyopathies also occur as a result of mutations in the TNN13 gene. Source: Troponin I, Cardiac from Human heart. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.