T8416-72

5-Trifluorothymidine

Size

£249.00

SKU:: T8416-72
Molecular Weight:: 296.2
Purity:: ≥99.5% (HPLC)
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 70-00-8
Format:: White crystalline powder
Extra Details:: Trifluorothymidine is an inhibitor of TS (thymidylate synthase). It is also a substrate used to study the specificity and kinetics of thymidine kinases. Acts as an anti-herpesvirus drug by blocking viral DNA replication. Decreases CRISPR-mediated HDR (homology-directed repair) efficiency. Synonyms: Trifluridine; Trifluorothymine Deoxyriboside; α,α,α-Trifluorothymidine; 2’-Deoxy-5-(trifluoromethyl)uridine; 5-(Trifluoromethyl)-2’-deoxyuridine; Viroptic CAS No: 70-00-8 Molecular Formula: C₁₀H₁₁F₃N₂O₅ Molecular Weight: 296.20 Appearance: White crystalline powder Purity: ≥99.5% (HPLC) Infrared Spectrum: Conforms to structure Loss on Drying: ≤1% 5-(Trifluoromethyl)uracil: ≤1% UV Max: 260nm Optical Rotation: [a]D20 = + 49 ± 2º (C=0.3% in H2O) Melting Point: 186-189°C Solubility: Methanol (Slightly), DMSO (>25 mg/ml), H₂O (>10mg/ml) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.