T8319-04A

TRIAD3, CT (E3 Ubiquitin-protein Ligase RNF216, RING Finger Protein 216, Ubiquitin Conjugating Enzyme 7 Interacting Protein 1, Triad3 Protein, Zinc Finger Protein Inhibiting NF-kappa-B, Triad Domain-containing Protein 3, UBCE7IP1, RNF216, ZIN)

Size

£696.00

SKU:: T8319-04A
Purity:: Purified by ammonium sulfate precipitation.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 716-745 from the C-terminal region of human TRIAD3.
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: UBCE7IP1 is a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Paraffin): 1:50-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.