T8282-40C
TREML2 (Trem-like Transcript 2 Protein, TLT-2, Triggering Receptor Expressed on Myeloid Cells-like Protein 2, Tlt2)
Size
£780.00
- SKU:
- T8282-40C
- Application:
- Flow Cytometry
- Purity:
- Purified by Protein G affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rat
- Immunogen:
- Recombinant corresponding to aa25-270 from mouse TREML2 expressed in CHO-S cell line.
- Clone:
- 12K189
- Format:
- Supplied as a lyophilized powder in PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.
- Extra Details:
- TREML2, also called TLT-2 is a 33kD type I transmembrane cell surface receptor and member of the Trem family of receptor proteins. Mouse TLT-2 is synthesized as a 329aa precursor that contains a 24aa signal sequence, a 246aa extracellular domain (ECD), a 21aa transmembrane segment, and a 38aa cytoplasmic tail. Within the ECD are an Ig-like V-type domain aa25-126 and one potential site for N-linked glycosylation. Mature mouse TLT-2 shares 49% aa sequence identity with mature human TLT-2. Cell surface expression of TLT-2 is seen for most of the B and myeloid cell lines. TLT-2 is also expressed constitutively on CD8+ T cells. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution:: Flow Cytometry: 2.5ug labels 10e6 cells Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice