T8180-01J

TRAIL (TNF Related Apoptosis Inducing Ligand, TNF-related Apoptosis-inducing Ligand TRAIL, Apo 2 Ligand, Apo2 Ligand, Apo-2 Ligand, Apo 2L, Apo2L, Apo-2L, CD253, CD253 Antigen, Protein TRAIL, TL2, Tumor Necrosis Factor (Ligand) Superfamily Member 10, TNFSF10, TNFSF10 Protein)

Size

£812.00

SKU:: T8180-01J
Purity:: Purified by Protein G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide (VLIVIFTVLLQSLCVAVTY) corresponding to aa17-35 of human TRAIL
Format:: Supplied as a liquid in PBS, pH 7.2.
Extra Details:: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) or Apo-2 ligand is a cytokine that belongs to TNF family and induces apoptosis of tumor cells by binding to its receptors, TRAIL R1 (DR4) and TRAIL R2 (DR5). Both Receptors contain death domains and two decoy receptors TRAIL-R3 (DcR1) and TRAIL-R4 (DcR2) that inhibit TRAIL function. TRAIL induces apoptosis and NF?B activation in many tissues and cells. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:100 Western Blot: 1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.