T8050-54A
TLR6 (Toll Like Receptor 6, Toll-like Receptor 6 Precursor, CD286)
Size
£812.00
- SKU:
- T8050-54A
- Purity:
- Purified by Protein G affinity chromatography from hybridoma culture supernatant.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rat
- Immunogen:
- HEK293 cells transfected with mouse TLR6, Phe39-Thr806
- Clone:
- 7H247
- Format:
- Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.
- Extra Details:
- TLR6 is a ~105kD cell surface type I transmembrane protein of the IL-1 receptor/Toll-like receptor (TLR) superfamily. TLRs are leucine-rich repeat-containing pattern recognition receptors for pathogen-associated molecular patterns that activate the innate immune system. TLR6 is expressed on macrophages, monocytes, neutrophils, and dermal endothelial cells in ligand-independent association with TLR-2. The mouse TLR6 extracellular domain shares 72%, and 86% aa identity with human and rat TLR6, respectively, and 59% aa with mouse TLR1. Applications: Suitable for use in Flow Cytometry and ELISA. Other applications not tested. Recommended Dilutions: Flow Cytometry: 0.25ug/10e6 cells using RAW 264.7 mouse monocyte/ macrophage cell line Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice