T8050-34G
TLR4 (Toll Like Receptor 4, CD284)
Size
£745.00
- SKU:
- T8050-34G
- Purity:
- Purified by Protein G affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- the Ba/F3 line expressing TLR4.
- Clone:
- 6A639 (HTA125)
- Format:
- Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.
- Extra Details:
- Toll-like receptors (TLR) are highly conserved throughout evolution and have been implicated in the innate defense to many pathogens. In Drosophila toll is required for the anti-fungal response, while the related 18-wheeler is involved in antibacterial defenses. In mammals, TLR identified as type I transmembrane signaling receptors with pattern recognition capabilities, have been implicated in the innate host defense to pathogens. TLR4 (CD284) has been identified next to MD-2 and CD14 as a receptor that is central to the innate immune response to lipopolysaccharides (LPS) of gram-negative bacteria. Applications: Suitable for use in Flow Cytometry, Functional Studies, ELISA, Immunofluorescence, Immunoprecipitation and Western Blot. Other applications not tested. Recommended Dilution: Flow Cytometry: 300,000 cells/50ul were stained with 2ug for 30 minutes at 4°C Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice