T5600-07

Tissue Plasminogen Activator (tPA), Recombinant, Human

Size

£842.00

SKU:: T5600-07
Molecular Weight:: 70
Purity:: ≥95% (SDS-PAGE)
Storage Conditions:: -70°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 0.4M HEPES, 0.1M sodium chloride, pH 7.4.
Extra Details:: Tissue Plasminogen Activator (tPA) is tissue specific for activation of plasminogen. The kringle-2 domain of tPA reacts with lysine residues on the fibrin forming an activated complex. tPA is a single chain molecule that is cleaved to the active two-chain form by the action of the plamin pathway. tPA primarily exists coupled to PAI-1 in circulation. tPA is completely complexable with human PAI-1 Specific Activity: As Reported Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.