T5579-01

Clavulanate Potassium, Streptomyces sp.

Size

£296.00

SKU:: T5579-01
Molecular Weight:: 237.25
Purity:: ~98% (HPLC)
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 61177-45-5
Format:: Supplied as a white to off-white powder
Extra Details:: Clavulanic acid is a beta-lactam antibiotic produced by several species of the genus Streptomyces. The free acid degrades and is isolated and maintained as either the sodium or potassium salt. Clavulanate is a weak antibiotic but is a potent inhibitor of beta- lactamases. In combination with penicillin and cephalosporins it shows potent synergistic activity. Clavulanic acid is a suicide inhibitor, covalently binding to a serine residue in the active site of the beta-lactamase. Source: Streptomyces sp. Solubility: Soluble in water, DMSO, Methanol, Ethanol and DMF. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.