THRA (Thyroid Hormone Receptor alpha, Nuclear Receptor Subfamily 1 Group A Member 1, V-erbA-related Protein 7, EAR-7, c-erbA-1, c-erbA-alpha, EAR7, ERBA1, NR1A1, THRA1, THRA2)

Size

£642.00

SKU:: T5348-98N
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Goat
Immunogen:: Synthetic peptide corresponding to C-KEEMIRSLQQRP, from human THRA, at the internal region of the protein (NP_955366.1, NP_003241.2).
Format:: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Extra Details:: Thyroid hormones regulate general metabolism and normal cellular growth and development. These actions are regulated by the thyroid hormone receptor (TR), a ligand-dependent transcriptional factor. At least two genes and several isoforms encode TR. Recent studies have implicated a role of TRs in thyroid hormone-induced apoptosis in larval tissues and proliferation of adult cell types. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:32,000 Western Blot: 0.5-1,5ug/ml, observed in human bone marrow lysates on ~60+50kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.