T5048-10B
THBD (Thrombomodulin, CD141, Fetomodulin, THRM, TM) (Biotin)
Size
£960.00
- SKU:
- T5048-10B
- Purity:
- Purified by Protein A affinity chromatography from hybridoma culture supernatant.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to Ala19-Ser515 of human Thrombomodulin expressed in NSO cells. Species Sequence Homology: Chimpanzee (98%), mouse (68%).
- Clone:
- 10K26
- Format:
- Supplied as a lyophilized powder from PBS, pH 7.4, with BSA. Labeled with Biotin. Reconstitute with 100ul sterile PBS.
- Extra Details:
- Thrombomodulin, also known as THBD, CD141 and BDCA-3, is an endothelial-specific type I membrane receptor that inhibits coagulation and fibrinolysis. It functions primarily as a cell surface receptor and an essential cofactor for active thrombin, resulting in the activation of protein C, which in turn degrades clotting factors Va and VIIIa. Mutations in this gene can cause inherited thrombophilia. The amino acid sequence of human Thrombomodulin is 98% and 68% aa identical to that of chimpanzee and mouse. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA (detection): 0.5-2ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice