T5047-01
Thromboglobulin, beta (Beta-Thromboglobulin, Beta-TG) (Not for Export EU)
Size
£704.00
- SKU:
- T5047-01
- Purity:
- Serum
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Highly purified human beta-Thromboglobulin isolated from platelets
- Format:
- Supplied as a lyophilized powder, 1mg/ml sodium azide. Reconstitute in 1ml sterile ddH2O. Dilute further in PBS, pH 7.2.
- Extra Details:
- Beta-thromboglobulin (β-thromboglobulin, also called Pro-Platelet basic protein or BTG) is a protein that is stored in alpha-granules of platelets and released in large amounts after platelet activation.[1] It is a type of Chemokine (C-X-C motif) ligand 7.[2] Beta-Thromboglobulin is a chemoattractant, strongly for fibroblasts and weakly for neutrophils. It is a stimulator of mitogenesis, extracellular matrix synthesis, glucose metabolism, and plasminogen activator synthesis in human fibroblasts.[1] Beta-Thromboglobulin also affects megakaryocyte maturation, and thus helps in regulating platelet production.[1] Levels of Beta-Thromboglobulin is used to index platelet activation. It is measured by ELISA in blood plasma or urine, and often in conjunction with Platelet factor 4)[1] It is elevated in diabetes mellitus.[3] Applications: Suitable for use in ELISA and Immunoprecipitation. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice