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T3786-15

Thiolutin (N-acetylpyrrothine, Farcinicine, Acetopyrrothine)

Size

£385.00

SKU:
T3786-15
Molecular Weight:
228.295
Purity:
> 98% by HPLC
Storage Conditions:
4°C/-20°C
Supplier:
United States Biological
CAS Number:
87-11-6
Format:
Yellow orange solid
Extra Details:
Thiolutin is an antibiotic first described by Tanner and co-workers in 1950. Resurgent interest in this class of microbial metabolite was stimulated by the discovery of their selective antitumor activity. Thiolutin has been shown to be a potent inhibitor of bacterial and yeast RNA polymerases and inhibitor of mannan and glucan formation in fungi. Studies have shown that thiolutin suppresses tumor cell-induced angiogenesis in vivo. DMSO and DMF, partially soluble in methanol and ethanol while poorly soluble in water
Shipping Conditions:
Blue Ice