T3700-01
THAP11 (THAP Domain Containing 11, Ronin, CTG-B43a, CTG-B45d, HRIHFB2206)
Size
£448.00
- SKU:
- T3700-01
- Purity:
- Purified by peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Goat
- Immunogen:
- Synthetic peptide corresponding to C-GSDHSYSLSSGTTEE, from the internal region of human THAP11 (NP_065190.2)
- Format:
- Supplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
- Extra Details:
- The protein encoded by this gene contains a THAP domain, which is a conserved DNA-binding domain that has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases. THAP11, also known as Ronin, is a 3644kD member of the Thanatos-associated protein family. It is ubiquitously expressed and through its repression of cMyc transcription, blocks cell proliferation. Human THAP11 is 314aa in length. It contains a DNA binding THAP zinc-finger domain (aa5-81), an NLS (aa98-104 a polyGln region (aa104-146 an Ala-rich segment (aa 197-221 and a C-terminal coiled coil region (aa255-305 THAP11 is phosphorylated on Thr25. Over aa226-314 human and mouse THAP11 are 100% identical in aa sequence. Applications: Suitable for use in ELISA. Other applications have not been tested. Recommended Dilutions: Peptide ELISA Titer: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice