Tetradecylthioacetic Acid

Size

£390.00

SKU:: T2967-01
Molecular Weight:: 288.49
Purity:: ~90%
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 2921-20-2
Format:: Supplied as a white solid.
Extra Details:: TTA is a novel thio-fatty acid which cannot undergo beta-oxidation. It induces apoptosis in IPC-81 leukemia cells via depolarization of mitochondrial membrane potential and inhibits glioma cell proliferation. TTA completely prevents high fat diet-induced insulin resistance and adiposity in Wistar rats. Activates rodent PPAR’s with rank order PPARα>PPARδ>PPARγ. Synonyms: TTA; 1-Mono(carboxymethylthio)tetradecane CAS No: 2921-20-2 Molecular Weight: 288.49 Molecular Formula: C16H32O2S Melting Point: 63-66°C Solubility: Dichloromethane (Slightly), DMSO (Slightly) Method for Determining Identity: Proton NMR Spectroscopic Analysis and Mass Spectrometric Analysis TLC Conditions: SiO2; Dichloromethane: Methanol: Acetic Acid; 9.5ml: 0.5ml: 10drops; Visualized with UV and AMCS; Single spot Rf=0.65. Appearance: Supplied as a white solid. Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.