TCCR, CT (T Cell Cytokine Receptor, WSX-1) (MaxLight 550)

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£947.00

SKU:: T2009-04A-ML550
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: 4°C Do Not Freeze
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to amino acids near the carboxy terminus of human TCCR precursor.
Format:: Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™550.
Extra Details:: MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000. TCCR (T cell cytokine receptor), otherwise known as Interleukin-27 Receptor Alpha. It is a member of the type I cytokine receptor family with higher levels of expression in CD4+ T cells than in CD8+ T cells. It is a receptor for Interleukin-27 and is involved in the regulation of Th1-type T cells. It also appears to be involved in innate defense mechanisms. TCCR is highly expressed in lymphoid tissue such as spleen, lymph nodes and peripheral blood leukocytes. It is also weakly expressed in tissues such as the heart, brain and lung. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.5-1.0ug/ml ~70kD in human spleen tissue lysates. Immunohistochemistry (Paraffin): 5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

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