S9111-40B1
Syndecan 2
Size
£812.00
- SKU:
- S9111-40B1
- Purity:
- Purified by Protein G affinity chromatography from hybridoma culture supernatant
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rat
- Immunogen:
- Recombinant protein corresponding to Glu19-Gly144 of human Syndecan-2 expressed in NS0 cells
- Clone:
- 7H78
- Format:
- Supplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 200ul sterile PBS.
- Extra Details:
- Syndecans are cell surface heparan sulfate proteoglycans that act as co-receptors for growth factor binding, cell-matrix interactions, and cell-cell interactions to regulate cell adhesion, proliferation, and differentiation. Syndecan-2 interacts with matrix proteins such as laminin and fibronectin, and its cytoplasmic V region controls matrix assembly at the cell surface. Syndecan-2 is essential for angiogenic sprouting during embryogenesis and controls the growth of normal human osteoblastic cells. Syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. Applications: Suitable for use in Direct ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry: 5-25ug/ml Detects Syndecan-2 in immersion fixed paraffin-embedded human prostate tissue. Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice