S8500-01D

Survivin, Recombinant, Human (BIRC5, Baculoviral IAP repeat-containing 5), API4, EPR-1)

Size

£586.00

SKU:: S8500-01D
Molecular Weight:: 33
Purity:: ≥90% by SDS-PAGE
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 20mM Tris pH 7.5, 0.1M sodium chloride
Extra Details:: Survivin is a human gene that is part of the inhibitor of apoptosis family (IAP). The Survivin protein functions to inhibit caspase activation therefore leading to negative regulation of apoptosis or programmed cell death. Recombinant human Survivin fused to CaM-tag at N-terminus was expressed in E.coli and purified by conventional chromatography techniques. Recombinant protein corresponding to aa1-142 from human Survivin fused to CaM-tag at the N-terminal expressed in E. coli. Amino Acid Sequence: MADQLTEEQI AEFKEAFSLF DKDGDGTITT KELGTVMRSL GQNPTEAELQ DMINEVDADG NGTIDFPEFL TMMARKMKDT DSEEEIREAF RVFDKDGNGY ISAAELRHVM TNLGEKLTDE EVDEMIREAD IDGDGQVNYE EFVQMMTAKG SHMGAPTLPP AWQPFLKDHR ISTFKNWPFL EGCACTPERM AEAGFIHCPT ENEPDLAQCF FCFKELEGWE PDDDPIEEHK KHSSGCAFLS VKKQFEELTL GEFLKLDRER AKNKIAKETN NKKKEFEETA KKVRRAIEQL AAMD Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.