Sulindac Sulfide

Size

£429.00

SKU:: S8025-31
Molecular Weight:: 340.41
Purity:: ~90%
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 32004-67-4
Format:: Yellow to Orange Solid
Extra Details:: An active metabolite of Sulindac. Inhibits cyclooxygenase, but induces apoptosis by a cyclooxygenase-independent mechanism. Inhibition of Ras activation of Ref-1. Impairs nucleotide exchange on Ras by CDC25 and accelerates Ras hydrolysis of GTP by p120GAP. CAS No: 32004-67-4 Molecular Formula: C₂₀H₁₇FO₂S Melting Point: 177-182°C Solubility: DMSO (Slightly), Methanol (Slightly, Heated) Method for Determining Identity: Proton NMR Spectroscopic Analysis TLC Conditions: Dichloromethane: Methanol; 9:1; Visualized with UV and AMCS; Single spot; Rf = 0.56. Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.