S7975-51D
Stromal Cell Derived Factor 1 alpha, Recombinant, Mouse (SDF1 alpha, SDF1a, SDF-1a, Chemokine (C-X-C Motif) Ligand 12, CXCL12, hIRH, Pre-B cell Growth-stimulating Factor, PBSF, SCYB12, TLSF-a, TPAR1)
Size
£554.00
- SKU:
- S7975-51D
- Molecular Weight:
- 7.9
- Purity:
- ≥98% (SDS PAGE and HPLC). Endotoxin: ≤1EU/ug
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Format:
- Supplied as a lyophilized powder. No stabilizing proteins added. No preservative added. Reconstitute in 100ul distilled water.
- Extra Details:
- SDF-1 alpha, otherwise known as CXCL12a, is a stromal cell derived CXC chemokine which, together with SDF-1 beta, arises from alternative splicing of the SDF-1 gene, and acts as a chemoattractant for T and B lymphocytes, monocytes and migratory neurons. SDF-1 binds with high-affinity to the G protein–coupled receptor CXCR4 (fusin), and acts as an inhibitor of the CXCR4-mediated entry of HIV-1 virus into target T-cells. Source: E. coli Applications: Suitable for use in Functional Assays. Other applications not tested. Biological Activity: Determined by its ability to chemoattract human peripheral blood monocytes, using a concentration of 50-100ng/ml. Molecular Weight: 7.9kD (68 amino acid residue homodimer) Amino Acid Sequence: KPVSLSYRCP CRFFESHIAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNK Storage and Stability: Lyophilized and reconstituted products may be stored at -20°C. Stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice