S5998-09

SPPL3, NT (Signal Peptide Peptidase-like 3, SPP-like 3, Intramembrane Protease 2, IMP-2, Presenilin-like Protein 4, IMP2, PSL4)

Size

£696.00

SKU:: S5998-09
Purity:: Purified by ammonium sulfate precipitation.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 50-81 in the N-terminal region of human SPPL3, UniProt Accession #Q8TCT6.
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: Signal peptide peptidase (SPP) is an aspartyl protease that mediates clearance of signal peptides by proteolysis within the endoplasmic reticulum (ER). Like presenilins, SPP contains a critical GXGD motif in its C-terminal catalytic center. SPPL3 is one of several presenilin homologues/SPP-like proteins (PSHs/SPPL) that have been identified. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.