S5451-20

SAP, ID (E300) (Proactivator Polypeptide, Saposin-A, Protein A, Saposin-B-Val, Saposin-B, Sphingolipid Activator Protein 1, SAP-1, Cerebroside Sulfate Activator, CSAct, Dispersin, Sulfatide/GM1 Activator, Saposin-C, Co-beta-glucosidase, A1 Activator, Glucosylceramidase Activator, Sphingolipid Activator Protein 2, SAP-2, Saposin-D, Protein C, Component C, SAP1, GLBA, PSAP)

Size

£696.00

SKU:: S5451-20
Purity:: Purified by ammonium sulfate precipitation.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 285-314 in the central region of human SAP, UniProt Accession #NP_002769; P07602.
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: PSAP is a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.