Spectrin, beta 2 (Spectrin beta Chain Brain 2, Spectrin beta Non-erythrocytic 2, SPTBN2, Spectrin Non-erythroid beta Chain 2, Spinocerebellar Ataxia 5, SCA5)

Size

£633.00

SKU:: S5380-15
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: The epitope recognized by this antibody maps to a region between residues 2150 and 2200 of human spectrin, beta, non-erythrocytic 2 (spinocerebellar ataxia 5) using the numbering given in entry NP_008877.1
Format:: Supplied as a liquid.
Extra Details:: Mutations in spectrins are a previously unknown cause of ataxia and neurodegenerative disease that affect membrane proteins involved in glutamate signaling. Spectrin-beta IIs have been recognized as ataxia disease genes and their mutations cause spinocerebellar ataxia type 5 (SCA5). Applications: Suitable for use in Immunohistochemistry and Immunoprecipitation. Other applications not tested. Recommended Dilution: Immunohistochemistry: 2.5-5ug/ml Immunoprecipitation: 2-5ug/mg lysate Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.