S4600
Sodium Butyrate, 1M (Histone Deacetylase Inhibitor)
Size
£342.00
- SKU:
- S4600
- Molecular Weight:
- 110.09
- Purity:
- 90-100%
- Storage Conditions:
- 4°C
- Supplier:
- United States Biological
- CAS Number:
- 156-54-7
- Format:
- Supplied as a liquid in 1M solution in sterile distilled water.
- Extra Details:
- A short chain fatty acid shown to be an inhibitor of histone deacetylase (HDAC). Induce apoptosis in colon carcinoma cell lines in a p53-independent pathway. Inhibits c-myc splicing and inteferes with signal transduction processes, including the release of Ca2+ from intracellular stores. Downregulates the activity of serine/threonine protease kinase casein kinase II in HT29 cells. Sodium Butyrate: CAS Number: 156-54-7 Molecular Formula: C₄H₇NaO₂ Molecular Weight: 110.09 Applications: For use as a histone deacetylase inhibitor. Recommended Dilutions: 1, 5, 20 and 100mM showed >70% inhibition of HDAC activity in HeLa nuclear extract using H5109-62: Histone Deacetylase (HDAC), BioAssay™ Fluorometric Detection Kit. Optimal dilutions to be determined by the researcher. Storage and Stability: Store at 4°C. Stable for 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Shipping Conditions:
- Blue Ice