S1014-18V
Slitrk6, CT (SLIT and NTRK-like family 6, FLJ22774, FLJ22774, MGC119595, MGC119596, MGC119597, SLIT and NTRK-like protein 6 precursor)
Size
£655.00
- SKU:
- S1014-18V
- Application:
- WB
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide corresponding to 16aa from near the carboxy terminus of human Slitrk6 (GenBank accession no. Q9H5Y7).
- Format:
- Supplied as a liquid in PBS, 0.02% sodium azide.
- Extra Details:
- SLIT and NTRK-like family 6 (Slitrk6) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains (1). Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family (1,2). Slitrk6 expression has been observed in tissues such as tongue, lung, gastrointestinal tract, and pancreas (3). Like every other Slitrk protein except Slitrk1, overexpression of Slitrk6 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5–1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice