S1014-16D

SKP1, ID (S-phase Kinase-associated Protein 1, Cyclin A/CDK2-associated Protein p19, p19A, p19skp1, RNA Polymerase II Elongation Factor-like Protein, Organ Of Corti Protein 2, OCP-II Protein, OCP-2, Transcription Elongation Factor B, SIII, SKP1A, EMC19, OCP2, SKP1, TCEB1L)

Size

£696.00

SKU:: S1014-16D
Purity:: Purified by ammonium sulfate precipitation.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 58-87 in the central region of human SKP1, UniProt Accession #NP_008861; P63208. Species sequence homology: bovine, chicken, monkey mouse, rat, Xenopus
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: SKP1A is an F-box protein which functions as a substrate recognition component of the SCF ubiquitin ligase complex. It binds to cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin proteolysis through an F-box motif. SKP1A also collaborates with a network of proteins to control beta-catenin levels and affects the activity level of beta-catenin dependent TCF transcription factors. Studies have also characterized the protein as an RNA polymerase II elongation factor. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.