S1014-15C

SKP1, aa1-160, Recombinant, Human (S-phase kinase-associated protein, EMC19, MGC34403, OCP-II, OCP2, p19A, SKP1A, TCEB1L)

Size

£453.00

SKU:: S1014-15C
Application:: WB
Purity:: ~90% by SDS-PAGE
Storage Conditions:: 4°C
Supplier:: United States Biological
Format:: Supplied as liquid in 20mM Tris-HCl buffer, pH8.0, 50mM NaCl, 10% glycerol.
Extra Details:: S-phase kinase-associated protein 1, also known as SKP1, is an F-box protein which functions as a substrate recognition component of the SCF ubiquitin ligase complex. It binds to proteins containing an F-box motif, such as cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin dependent proteolysis. It is also involved in the control of beta-catenin levels and the activity of beta-catenin dependent TCF transcription factors. Recombinant human SKP1 protein was expressed in E.coli and purified by using conventional chromatography techniques. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Molecular Weight: 18kD (160aa) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.