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S1013-88A6

SIRT1 (NAD-dependent Deacetylase Sirtuin-1, hSIRT1, SIR2-like Protein 1,SIR2L1 Sirtuin (Silent Mating Type Information Regulation 2 Homolog) 1 (S. cerevisiae), hSIR2, SIR2L1) (Azide Free)

Size

£685.00

SKU:
S1013-88A6
Purity:
Purified by immunoaffinity chromatography.
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Mouse
Immunogen:
Partial recombinant protein corresponding to a portion of amino acids within aa456-555, from human SIRT1 with GST tag. GST tag alone is 26kD.
Clone:
11C756
Format:
Supplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).
Extra Details:
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. [provided by RefSeq] Applications: Suitable for use in Immunofluorescence and Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 1:500-1:1000 Immunofluorescence: 10ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Shipping Conditions:
Blue Ice