Simvastatin-d6

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£351.00

SKU:: S1013-85H
Molecular Weight:: 424.6
Purity:: ≥95%
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 1002347-71-8
Format:: White to off-white solid
Extra Details:: Deuterated Simvastatin, a competitive inhibitor of HMG-CoA reductase. A deuterated synthetic analog of lovastatin. Simvastatin is a synthetic derivative of a fermentation product of Aspergillus terreus. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor. Synonyms: 2,2-(Dimethyl-d6)butanoic Acid(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro_x000B_-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]_x000B_-1-naphthalenyl Ester; (+)-Simvastatin-d6; Cholestat-d6; Lipex-d6; Novo-Simvastatin-d6; Simvotin-d6; Sinvacor-d6; Statin-d6; Zocor-d6; Zorced-d6 CAS No: 1002347-71-8 Unlabeled: 79902-63-9 Molecular Formula: C₂₅H₃₂D₆O₅ Molecular Weight: 424.6 Appearance: White to off-white solid Purity: ≥95% Solubility: Chloroform (Slightly), Methanol (Slightly) Melting Point: 117-121˚C Method for Determining Identity: 1H NMR (CDCL3) and Mass Spectrometric Analysis TLC Conditons: SiO2; Dichloromethane: Methanol: = 9 : 1; Visualized with UV and KMnO4; Single Spot, Rf=0.60 Normalized Intensity: d0=0.10%, d1=0.00%, d2=0.01%, d3=0.00%, d4 =0.17%, d5=0.27%, d6=99.46%, Elemental Analysis: Calculated: %C:70.72, %H:9.02 Specific Rotation (c=0.1, methanol): As reported Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C for 6 months after receipt. Hygroscopic, Under Inert Atmosphere. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.

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