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S1013-57A

Siglec 1 (Sialic Acid Binding Ig-like Lectin 1, CD169, CD169 Antigen, dJ1009E24.1, DKFZp667F058, FLJ00051, FLJ00055, FLJ00073, FLJ00411, FLJ32150, Sialic Acid-binding Ig-like Lectin 1, Sialic Acid-binding Ig-like Lectin-1, Sialoadhesin, Sialoadhesin Precursor, Siglec 1, SN)

Size

£594.00

SKU:
S1013-57A
Purity:
Purified by Protein G affinity chromatography.
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Mouse
Immunogen:
Full-length purified human Siglec-1(d1-4)Fc protein. Cellular Localization: Isoform 1: cell membrane; Single-pass type-1 membrane protein; Isoform2: secreted. Species Sequence Homology: porcine, virus, and mouse.
Clone:
9E697
Format:
Supplied as a liquid in PBS, 0.05% sodium azide.
Extra Details:
The siglecs are a family of membrane bound lectins (of the immunoglobulin superfamily) that bind sialic acid and mediate cell-cell interactions. Family members include sialoadhesin, CD22 and CD33. Sialoadhesin is a macrophage-specific cell adhesion molecule that is expressed on activated macrophages in chronic inflammation and in tumors. Applications: Suitable for use in Western Blot, RIA, Flow Cytometry, ELISA, Immunofluorescence/Immunocytochemistry and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry (frozen): 1:10-1:500 Immunohistochemistry (paraffin): 1:10-1:500 Immunohistochemistry: 1:10-1:500 Flow Cytometry: 1:10-1:1000 Immunofluorescence (IC): 1:10-1:500 ELISA: 1:100-1:2000 Western Blot: 1:100-1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Shipping Conditions:
Blue Ice