S1013-34A
Sialoprotein, Bone (BSP) (Not for Export EU)
Size
£825.00
- SKU:
- S1013-34A
- Purity:
- Serum
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Purified human Bone sialoprotein
- Format:
- Supplied as a liquid. No preservatives added.
- Extra Details:
- Bone sialoprotein (BSP) is one of the major noncollagenous proteins in the extracellular matrix of bone. It is a phosphorylated glycoprotein with an MW ~70-80kD. The protein has been found in osteoblasts and osteocytes. BSP is synthesized and secreted by bone-, dentin- and cementum-forming cells. Diseases concerning the bone turnover, pathological bone alterations as well as the rapid increase of osteoporosis make it necessary to establish new markers. Bone sialoprotein is discussed as a potential serum marker for monitoring bone remodelling. Applications: Suitable for use in Western Blot, Immunohistochemistry, RIA and ELISA. Other applications have not been tested. Recommended Dilutions: Immunohistochemistry: 1:2500 using 5um paraffin embedded sections from human fetal tibia, fetal calvaria and metastatic breast tumors to bone; with decalcification with 10% formic acid Optimal dilutions to be determined by the researcher. Recommended Secondary Antibodies: IHC I1904-43: IgG, X-Adsorbed (Biotin) Pab GtxRb I1904-40E: IgG, H&L (Biotin) Pab GtxRb I1904-46P: IgG, H&L (Biotin) Pab GtxRb Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice