S0747-01

SENP8, NT (Sentrin-specific Protease 8, Sentrin/SUMO-specific Protease SENP8, Protease, Cysteine 2, NEDD8-specific Protease 1, Deneddylase-1, DEN1, NEDP1, PRSC2, FKSG8)

Size

£696.00

SKU:: S0747-01
Purity:: Purified by ammonium sulfate precipitation.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 4-35 in the N-terminal region of human SENP8, UniProt Accession #Q96LD8; Q9D2Z4; NP_660205.
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: NEDD8 is a ubiquitin-like protein that becomes conjugated to the cullin subunit of several ubiquitin ligases. This conjugation, called neddylation, is required for optimal ubiquitin ligase activity. SENP8 is a protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.