S0097-50
Saracatinib, Free Base (N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(oxan-4-yloxy)quinazolin-4-amine, AZD-0530)
Size
£194.00
- SKU:
- S0097-50
- Molecular Weight:
- 542.03
- Purity:
- HPLC: ~99%. TLC: ~99%
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- CAS Number:
- 379231-04-6
- Format:
- Supplied as a white to off-white crystalline powder.
- Extra Details:
- Saracatinib an orally available Src kinase inhibitor. Saracatinib inhibits c-Src and Abl enzymes at low nanomolar concentrations. Saracatinib blocked the tumor growth of a c-Src-transfected 3T3-fibroblast xenograft in vivo and increased significantly the survival of animals in a highly aggressive model of human pancreatic cancer. Solubility: Soluble in DMSO at 200mg/ml; soluble in ethanol at 200mg/ml; very poorly soluble in water; maximum solubility in plain water is estimated to be about 20-100uM; buffers, serum, or other additives may increase or decrease the aqueous solubility. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 6 months after receipt.
- Shipping Conditions:
- Blue Ice