S0058-50

Salinomycin

Size

£353.00

SKU:: S0058-50
Molecular Weight:: 751
Purity:: ≥95% (HPLC)
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 53003-10-4
Format:: Supplied as a white solid.
Extra Details:: Salinomycin is a polyether ionophore with broad spectrum Gram +ve and anti-coccidial activity. Salinomycin has a high affinity for monovalent cations, particularly potassium. Salinomycin is used in animal health for control of coccidia and for growth promotion in ruminants. Recently, salinomycin has been shown to inhibit cancer stem cells and is > 100 times more potent than taxol. While the mechanism of action is unknown, it was noted that among the 60,000 compounds screened, another monovalent ionophore, nigericin, and a chloride channel inhibitor, avermectin, were also active. Source: Salinomycin from Streptomyces sp. Molecular Weight: 751D Solubility: Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 6 months at -20°C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.