R9985
RXR alpha, aa111-228, Recombinant, Human (Retinoid X Receptor alpha)
Size
£819.00
- SKU:
- R9985
- Molecular Weight:
- 13.6
- Purity:
- ≥ 95% by SDS PAGE; Purified by conventional column chromatography techniques.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Format:
- Supplied as a liquid in 20mM Tris-HCl, pH 7.5, 0.1M sodium chloride and 5mM beta-Mercaptoethanol.
- Extra Details:
- The retinoid X receptor (RXR) is a pleiotropic nuclear receptor transcription factor that interacts with a variety of nuclear receptor dimeric partner. RXR binds cognate response elements as a homodimer in the presence of its ligand, 9-cis retinoic acid, or as a heterodimer with other members of the nuclear hormone receptor superfamily including retinoic acid receptors (RAR), thyroid hormone receptors (TR), vitamin D receptors and peroxisome proliferators-activated receptors (PPAR). The RXR family includes three difference isoforms; RXR alpha, beta, gamma. Human RXR alpha gene is localized on 9q34.9 and encodes two major isoforms (RXRa1, RXRa2). The DNA binding domain of RXR (111-228aa) was overexpressed in E.coli. Molecular Weight: 13.6kD (119 amino acids) Sequence: MLGLNGVLKV/ PAHPSGNMAS/ FTKHICAICG/ DRSSGKHYGV/ YSCEGCKGFF/ KRTVRKDLTY/ TCRDNKDCLI/ DKRQRNRCQY/ CRYQKCLAMG/ MKREAVQEER/ QRGKDRNENE/ VESTSSANE Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice