Robo4 (Roundabout Homolog 4, Roundabout Homolog 4 Magic Roundabout, Roundabout Homolog 4 Precursor, FLJ20798, Magic Roundabout, MRB, MGC133352, MGC133353)

Size

£594.00

SKU:: R9417-73A
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to to a C-terminal region of the human protein (within residues 900-1007).
Format:: Supplied as a liquid in Tris-citrate/phosphate, pH 7-8, 0.09% sodium azide.
Extra Details:: Roundabouts (ROBO) are cell-surface receptors that mediate repulsive signaling mechanisms at the central nervous system midline. However, ROBOs may also mediate attraction mechanisms in the context of vascular development. ROBO4 is a novel roundabout protein which is restricted in expression to endothelial cells in vitro and sites of angiogenesis in vivo. Because it is not expressed on normal endothelial cells, in vivo, it is a promising tumor endothelial marker. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Positive Control: HUVEC lysate Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.