Ridaforolimus

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£332.00

SKU:: R2031-62Y
Molecular Weight:: 990.21
Purity:: ≥80%
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 572924-54-0
Format:: Off-white to pale yellow solid
Extra Details:: Ridaforolimus (the name has been changed from "deforolimus") is an immunosuppressant and a novel small-molecule inhibitor of the protein mammalian target of rapamycin (mTOR). Ridaforolimus inhibits cancer cell growth, cell division, metabolism, and angiogenesis by blocking mTOR. Synonyms: 42-(Dimethylphosphinate)rapamycin; 9CI; AP 23573; Deforolimus; MK-8669; (1R,2R,4S)-4-[(2R)-2-[(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28Z,30S,32S,35R)-1,18-dihydroxy-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-2,3,10,14,20-pentaoxo-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraen-12-yl]propyl]-2-methoxycyclohexyl dimethylphosphinate CAS No: 572924-54-0 Molecular Formula: C₅₃H₈₄NO₁₄P Molecular Weight: 990.21 Appearance: Off-white to pale yellow solid Purity: ≥80% NMR: Conforms to Structure Elemental Analysis: s%C: 63.18, %H: 8.50, %N: 1.52 Conforms MS: Conforms to Structure Specific Rotation: 124.1° (c = 0.1, Methanol) P NMR: Conforms to Structure Melting Point: 95-98°C Solubility: DMSO (Slightly), Methanol (Slightly) Storage and Stability: May be stored at RT for short-term only. Hygroscopic. Under Inert Atmosphere. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Shipping Conditions:: Blue Ice