R2031-59A-PE

RICK, NT (RIP2, CARDIAK, RIP-like Interacting CLARP Kinase, Receptor Interacting Protein-2, Receptor-Interacting Serine/Threonine-Protein Kinase 2, RIP-2, CARD-Containing IL-1 beta ICE-Kinase, UNQ277/PRO314/PRO34092, CARD-containing ICE Associated Kinase) (PE)

Size

£902.00

SKU:: R2031-59A-PE
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: 4°C Do Not Freeze
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to aa near the amino terminus of human RIP2.
Format:: Supplied as a liquid in PBS, pH 7.2. Labeled with R-Phycoerythrin (PE).
Extra Details:: Receptor-interacting kinase (RIP2) is a 61.2kD cytoplasmic protein belonging to the protein kinase superfamily. It is a novel kinase that regulates TNF and Fas induced-apoptosis and is involved in the generation of the pro-inflammatory cytokine IL-1beta. Over expression of RIP2 has been shown to induce apoptosis, and the activation of NF-Kappa-B and JNK. RIP2 is widely expressed in a range of human tissues. Applications: Suitable for use in Immunohistochemistry (frozen) and Western Blot. Other applications not tested. Recommended Dilution: Immunohistochemistry (frozen): 10ug/ml Western Blot: 0.5-1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.