RTEL1, NT (Regulator of Telomere Elongation Helicase 1, Novel Helicase-like, C20orf41, KIAA1088, NHL)

Size

£665.00

SKU:: R1642-40
Purity:: Purified by immunoaffinity chromatography
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to residues of the N-terminal of human RTEL1
Format:: Supplied as a liquid in PBS, 0.01% sodium azide, 50% glycerol
Extra Details:: RTEL1 (Regulator of telomere elongation helicase 1) is probably an ATP-dependent DNA helicase. RTEL1 is a member of the stathmin family, and is related to RAD3/ERCC2, a plasma membrane Ras-related GTPase. The amplification or overexpression of this gene may contribute to cell growth and tumor progression. It is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes, such as TNFRSF6B. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: ELISA: 1ug/ml Western Blot: 1ug/ml Immunohistochemistry (FFPE): 5ug/ml. Heat induced antigen retrieval in citrate buffer, pH 6.0 is required Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.