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R1585-36-PE

Resistin (PE)

Size

£735.00

SKU:
R1585-36-PE
Purity:
Purified by immunoaffinity chromatography.
Storage Conditions:
4°C Do Not Freeze
Supplier:
United States Biological
Host:
Rabbit
Immunogen:
Synthetic peptide, aa79-90 [GSWDVRAETTCH] of the human Resistin protein.
Format:
Supplied as a liquid in PBS, pH 7.2. No preservative added. No stabilizing proteins added. Labeled with R-Phycoerythrin (PE).
Extra Details:
It has been suggested that the hormone resistin secreted by adipocytes, links obesity to type 2 diabetes by modulating steps in the insulin-signaling pathway and inducing insulin resistance. Levels of circulating resistin decrease following treatment with the anti diabetic drug rosiglitazone and increase in diet-induced and genetic forms of obesity. In addition, treatment of normal mice with recombinant resistin impairs glucose tolerance and insulin action. Insulin-stimulated glucost uptake by adipocytes is enhanced by neutralization of resistin and is reduced by resistin treatment. Applications: Suitable for use in FLISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
Shipping Conditions:
Blue Ice