R1585-36-ML490
Resistin (MaxLight 490)
Size
£735.00
- SKU:
- R1585-36-ML490
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- 4°C Do Not Freeze
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide, aa79-90 [GSWDVRAETTCH] of the human Resistin protein.
- Format:
- Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
- Extra Details:
- MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. It has been suggested that the hormone resistin secreted by adipocytes, links obesity to type 2 diabetes by modulating steps in the insulin-signaling pathway and inducing insulin resistance. Levels of circulating resistin decrease following treatment with the anti diabetic drug rosiglitazone and increase in diet-induced and genetic forms of obesity. In addition, treatment of normal mice with recombinant resistin impairs glucose tolerance and insulin action. Insulin-stimulated glucost uptake by adipocytes is enhanced by neutralization of resistin and is reduced by resistin treatment. Applications: Suitable for use in FLISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Shipping Conditions:
- Blue Ice