RAPSN, CT (43kD Receptor-associated Protein of the Synapse, RAPsyn, 43kD Postsynaptic Protein, Acetylcholine Receptor-associated 43kD Protein, RING Finger Protein 205, RNF205)

Size

£709.00

SKU:: R1139-50D
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to C-terminal residues of human RAPSN (KLH).
Format:: Supplied as a liquid in PBS, 0.01% sodium azide, 50% glycerol.
Extra Details:: Rapsyn (receptor-associated protein of the synapse) is a peripheral membrane protein that has a close association to acetylcholine receptors (AChRs). Studies have shown that mice with a mutated rapsyn gene were unable to form AChR clusters, resulting in birth from respiratory failure death soon after. Other mutations affecting the activity of rapsyn can lead to the formation of the neuromuscular disease myasthenia gravis. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1ug/ml Immunohistochemistry (Formalin-fixed, paraffin-embedded): 10-20ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.