R1035-85
RepSox (SJN 2511, ALK5 Inhibitor II)
Size
£165.00
- SKU:
- R1035-85
- Molecular Weight:
- 287.32
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- CAS Number:
- 446859-33-2
- Extra Details:
- Alk 5 Inhibitor II is a selective ATP competitive inhibitor of transforming growth factor-β (TGFβ). A potential drug for the treatment of fibrosis and cancer.. Inhibits ALK5 autophosphorylation (IC₅₀=4nM). Can replace one of the four reprogramming factors Sox-2. RepSox has been successfully used in the direct reprogramming of mouse fibroblasts through induction of Nanog transcription. Synonyms: 2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine; E 616452; RepSox; SJN 2511; ALK5 Inhibitor II CAS No: 446859-33-2 Molecular Formula: C₁₇H₁₃N₅ Molecular Weight: 287.32 Purity (NMR): ≥98% Appearance: White to off-white, light brown solid Solubility: DMSO Method of Determining Identity: 1 H NMR Spectometry Storage and Stability: Store at -20°C. Stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Shipping Conditions:
- Blue Ice