R1031-16

Rage (Receptor for Advanced Glycosylation End Products, Advanced Glycosylation End Product-specific Receptor, Ager)

Size

£1,023.00

SKU:: R1031-16
Purity:: Purified by Protein G affinity chromatography from hybridoma culture supernatant.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rat
Immunogen:: Recombinant protein corresponding to Gly23-Ala342 of mouse RAGE, expressed in NSO cells.
Clone:: 8B42
Format:: Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 1ml sterile PBS.
Extra Details:: Receptor for Advanced Glycation End Products (RAGE), also named AGER (Advanced Glycosylation End Product-specific Receptor), is a member of the immunoglobulin superfamily. It binds multiple ligands including S100/calgranulins, amyloid fibrils, amphoterin and leukocyte integrins. Applications: Suitable for use in ELISA and Western Blot. Other applications have not been tested. Recommended Dilutions: ELISA (Capture): 2-8ug/ml using 058615 as detetction antibody. Western Blot: 2ug/ml under non-reducing conditions. Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.