P9181-91

PINK1 (Serine/Threonine-protein Kinase PINK1, Mitochondrial, BRPK, PTEN-induced Putative Kinase Protein 1)

Size

£642.00

SKU:: P9181-91
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Goat
Immunogen:: Synthetic peptide corresponding to C-QGKAHLESRSYQEAQ, from the internal region of human PINK1. Species Sequence Homology: rat
Format:: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Extra Details:: Mutations in the PTEN-induced kinase (PINK1) gene located within the PARK6 locus on chromosome 1p35-p36 have recently been identified in patients with recessive early-onset Parkinson disease. Data suggests that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Applications: Suitable for use in ELISA, Immunofluorescence and Flow Cytometry. Other applications not tested. Recommended Dilutions: ELISA (Peptide): 1:8000 Immunofluorescence: 10ug/ml. Strong expression of PINK1 in the mitochondria and endoplasmImmunocytochemistry reticulim of HeLa cells Flow Cytometry: 10ug/ml using MCF7 cells Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.