P9181-90L
PTEN-induced Kinase 1 (PTEN-induced Putative Kinase 1, PTEN-induced Putative Kinase Protein 1, PINK1, PINK-1, BRPK, FLJ27236, PARK6, Serine/threonine Protein Kinase PINK1 Mitochondrial)
Size
£607.00
- SKU:
- P9181-90L
- Application:
- WB
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- An N-terminal region synthetic peptide made to the human Pink1 protein sequence (between residues 1-50).
- Format:
- Tris-citrate/phosphate, [pH7-8].
- Extra Details:
- Phosphatase and Tensin Homolog (PTEN) dephosphorylates lipids. Malfunctions in this contribute to many human cancers. PTEN induced putative kinase 1 (Pink1) was first discovered when researching the PTEN signaling pathway, thus Pink1 is also involved in many human cancers. It is found in the mitochondria and its homozygous C-terminus mutation has been implicated in the early development of Parkinson's disease. Cellular Localization: Mitochondrion. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice